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SAB3500080 Sigma

Anti-SYPL1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-Synaptophysin-like 1 protein, Anti-H-SP1, Anti-Pantophysin

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies with Corresponding Blocking Peptides, Primary Antibodies, R-S,
species reactivity   mouse, rat, human
application(s)   indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... SYPL1(6856)
biological source   rabbit
conjugate   unconjugated
NCBI accession no.   NP_006745
UniProt accession no.   Q16563

Description

Immunogen

SYPL1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human SYPL1.

Antigen Background

The synaptophysin-like protein 1, also known as pantophysin, is a homolog of the neuroendocrine-specific protein synaptophysin, with the highest level of homology across its four transmembrane domains. Unlike synaptophysin however, SYPL1 is ubiquitously expressed and found in small cytoplasmic transport vesicles regardless of their content. SYPL1 is thought to play a multifunctional role in vesicle biogenesis and transport and is a component of adipocyte transport vesicles, and thus may be involved in adipocyte secretion. SYPL1 also interacts with vesicle-associated membrane protein 2 (VAMP-2) in adipocytes and associates with GLUT4-containing vesicles. This antibody will not recognize synaptophysin of SYPL2. Two isoforms of SYPL1 are known to exist; this antibody will only recognize the longer isoform.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500080.

Price and Availability


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Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles

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SBP3500080 SYPL1 Blocking Peptide for SAB3500080

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