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SAB3500085 Sigma

Anti-TMEM214 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution, ab1

Synonym: Anti-Transmembrane protein 214

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies with Corresponding Blocking Peptides, Primary Antibodies, T,
species reactivity   rat, human, mouse
application(s)   immunocytochemistry: suitable
  immunofluorescence: suitable
  indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... TMEM214(54867)
biological source   rabbit
conjugate   unconjugated
NCBI accession no.   NP_060197
UniProt accession no.   Q6NUQ4

Description

Immunogen

TMEM214 antibody was raised against a 17 amino acid peptide near the amino terminus of human TMEM214.

Antigen Background

Transmembrane protein 214 (TMEM214) is a 77kD membrane protein which is widely expressed at high level. The gene encoding this protein maps to chromosome 2, at 2p23.3 TMEM214 interacts with LSM1, an SM-like protein, forming a stable heteromer present in tri-snRNP particles, which are important for pre-mRNA splicing. The detailed function of TMEM214 is still unknown, but a recent study showed that TMEM214 may be used to explore the contribution of human host factors of some infectious diseases such as Dengue fever, West Nile fever and yellow fever. Multiple isoforms of TMEM214 are known to exist.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500085.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
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SBP3500085 TMEM214 (AB1) Blocking Peptide for SAB3500085

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