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SAB3500088 Sigma

Anti-TWA1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-Two hybrid-associated protein 1 with RanBPM

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies with Corresponding Blocking Peptides, Primary Antibodies, T,
species reactivity   mouse, rat, human
application(s)   immunofluorescence: suitable
  immunohistochemistry: suitable
  indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... C20orf11(54994)
biological source   rabbit
conjugate   unconjugated
NCBI accession no.   NP_060366
UniProt accession no.   Q9NWU2

Description

Immunogen

TWA1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human TWA1.

Antigen Background

TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500088.

Price and Availability


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Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles

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SBP3500088 TWA1 Blocking Peptide for SAB3500088

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