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  • SAB3500089 - Anti-PGCC1 antibody produced in rabbit

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SAB3500089 Sigma

Anti-PGCC1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-CCPG, Anti-Constitutive coactivator of PPAR-gamma 1, Anti-FAM120B

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies with Corresponding Blocking Peptides, N-P, PD-PG,
species reactivity   mouse, rat, human
application(s)   indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... FAM120B(84498)
biological source   rabbit
conjugate   unconjugated
NCBI accession no.   Q96EK7
UniProt accession no.   Q96EK7

Description

Immunogen

PGCC1 antibody was raised against an 18 amino acid peptide from near the carboxy terminus of human PGCC1.

Antigen Background

The transcription factor peroxisome proliferator-activated receptor gamma (PPARg) plays essential roles in adipogenesis by regulating adipocyte-specific genes through association of various co-factors. One such co-factor, PGCC1 (also known as FAM120B), is widely expressed in adult tissues and throughout embryonic development. Overexpression of this protein in OP9 pre-adipocytes promoted their differentiation into adipocytes, and knockdown of PGCC1 expression through RNA interference blocked this process. PGCC1 is homologous to C9orf10 (also known as FAM120A) and has been mapped to chromosome Xp11.22. At least two isoforms of PGCC1 are known to exist. This antibody will not cross-react with FAM120A.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500089.

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Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
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SBP3500089 PGCC1 Blocking Peptide for SAB3500089

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