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SAB3500107 Sigma

Anti-IA-6 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-Insulinoma-associated 2, Anti-INSM2, Anti-Mlt1

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies to Transcription Factors, Antibodies with Corresponding Blocking Peptides, Epigenetics,
species reactivity   mouse, human, rat
application(s)   indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... INSM2(84684)
biological source   rabbit
conjugate   unconjugated
NCBI accession no.   AAI30380
UniProt accession no.   Q96T92

Description

Immunogen

IA-6 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human IA-6.

Antigen Background

IA-6, also known as insulinoma-associated 2 or INSM2, is related to IA-1 (INSM1), a zinc-finger factor that is expressed in the developing nervous system. While the exact function of IA-6 is not known, other related insulinoma-associated proteins such as IA-2 are major autoantigens in type 1 diabetes. The homology exhibited by IA-6 to IA-1 has led to speculation that IA-6 may also play a role in the regulation of gene transcription.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500107.

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Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
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SBP3500107 IA-6 Blocking Peptide for SAB3500107

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