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SAB3500117 Sigma

Anti-OCIAD1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-OCIA domain-containing protein 1, Anti-Ovarian cancer immuno-reactive antigen domain-containing protein 1

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies with Corresponding Blocking Peptides, N-P, O,
species reactivity   human
application(s)   immunofluorescence: suitable
  indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... OCIAD1(54940)
biological source   rabbit
conjugate   unconjugated
NCBI accession no.   NP_060300
UniProt accession no.   Q9NX40

Description

Immunogen

OCIAD1 antibody was raised against a 16 amino acid peptide from near the carboxy terminus of human OCIAD1.

Antigen Background

OCIAD1 was identified via immunoscreening of an ovarian carcinoma cDNA library from ovarian cancer patients and is expressed in multiple tissues including ovary, placenta, brain, testis, prostate, and mammary gland. Two isoforms of OCIAD1 are known to exist; the shorter isoform is restricted to the central nervous system. OCIAD1 is a transmembrane protein whose overexpression in HEY ovarian cancer cells increased lysophosphatidic acid- (LPA-)induced, but not basal level cell adhesion to extracellular matrix proteins collagen I and laminin10/11. This adhesion is not blocked by LY294002 and GF109203X, suggesting that OCIAD1 does not use protein kinase C and PI3 kinase signaling pathways to exert its effect on adhesion.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500117.

Price and Availability


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Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles

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SBP3500117 OCIAD1 Blocking Peptide for SAB3500117

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