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SAB3500124 Sigma

Monoclonal Anti-CD4L antibody produced in mouse

clone 9H5A8, purified immunoglobulin, buffered aqueous solution

Synonym: Anti-CD4 antigen, Anti-CD4 receptor

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Properties

Related Categories Alphabetical Index, Antibodies, CD0-CDC, Primary Antibodies
biological source   mouse
antibody form   purified immunoglobulin
clone   9H5A8, monoclonal
form   buffered aqueous solution
species reactivity   mouse, rat, human
application(s)   immunohistochemistry: suitable
  indirect ELISA: suitable
  western blot: suitable
conjugate   unconjugated
UniProt accession no.   P01730
shipped in   dry ice
storage temp.   −20°C

Description

Antigen Background

CD4 is a member of the immunoglobulin superfamily and is implicated as associative recognition element in MHC (Major Histocompatibility Complex) class II-restricted immune response. On T-lymphocytes, it defines the helper/inducer subset. The mature 55 kd CD4 protein consists of a 372 amino acid extracellular segment composed of four tandem immunoglobulin-like VJ regions. The CD4 molecule is a major receptor for human immunodeficiency virus (HIV), binding directly to the envelope glycoprotein gp120 on HIV, with the co-receptors being CCR5 or CXCR4. It has been shown that the V-like domains are critical for binding with HIV envelope gp120.

Immunogen

raised against a 193 amino acid recombinant protein from near the amino terminus of human CD4.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
Protocols & Articles

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Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

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