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SAB3500209 Sigma

Anti-AGTR1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-AT1, Anti-AT1R, Anti-Ang II, Anti-Angiotensin II receptor type 1

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Properties

Related Categories A-B, AE-AK, Alphabetical Index, Antibodies, Antibodies with Corresponding Blocking Peptides,
species reactivity   mouse, human, rat
application(s)   immunofluorescence: suitable
  immunohistochemistry: suitable
  indirect ELISA: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... AGTR1(185)
biological source   rabbit
conjugate   unconjugated
NCBI accession no.   EAW78909
UniProt accession no.   P30556

Description

Immunogen

AGTR1 antibody was raised against a 16 amino acid peptide from near the center of human AGTR1.

General description

Angiotensin II receptor, type 1 or AT1 receptor (AGRR1, AT1R) is a receptor for the vasoconstriction peptide angiotensin II involved in the regulation of cardiovascular effects such as blood vasoconstriction (blood pressure), aldosterone and vasopressin secretion, cardiac hypertrophy, vascular smooth muscle cells proliferation, decreased renal blood flow, renal renin inhibition, renal tubular sodium reuptake, modulation of central sympathetic nervous system activity, cardiac contractility, central osmocontrol and extracellular matrix formation.

Rabbit polyclonal anti-AGTR1 reacts with mouse, human, and rat angiotensin II receptor.

Physical form

Supplied in PBS with 0.02% sodium azide.

Application

Rabbit polyclonal anti-AGTR1 is used to tag angiotensin II receptor for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques. It is used as a probe to determine the presence and roles of angiotensin II receptor in the regulation of processes that affect vascular functions such as blood pressure and blood flow.

Linkage

The action of this antibody can be blocked using blocking peptide SBP3500209.

Price and Availability


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Safety & Documentation

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  2
Protocols & Articles

Articles

Antihypertensive Agents

Download BioFiles v7 n5 (3.18 Mb PDF) Back to Pharmaceutical Drugs and Drug Candidates homepage
Sami Barghshoon
BioFiles v7 n5, 2012, 5–20
Keywords: AGE, Antihypertensives, Cardiovascular, Clinical, Diuretics, Pharmaceutical, Reductions

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SBP3500209 AGTR1 Blocking Peptide for SAB3500209

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