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SAB4200239 Sigma

Monoclonal Anti-Alpha4 antibody produced in mouse

~1 mg/mL, clone 5F6, purified immunoglobulin

Synonym: Anti-Immunoglobulin-binding protein 1, Anti-IGBP1

Properties

Related Categories AL-AL, Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology,
species reactivity   mouse, human
application(s)   western blot: 1-2 μg/mL using whole extracts of mouse 3T3 or human HeLa cells
clone   5F6, monoclonal
concentration   ~1 mg/mL
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG1
mol wt   antigen mol wt ~40 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... IGBP1(3476)
mouse ... Igbp1(18518)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

mouse Alpha4 fusion protein. The corresponding sequence shares 80% homology with human Alpha4.

General description

α 4 is a phosphoprotein that is expressed in a wide range of tissues, including pancreas, lymph node, thymus, kidney, leukocytes, fetal liver, heart, and brain. This phosporpotein associates with protein phosphatases 2A, 4, and 6 to regulate the rapamycin-sensitive pathway mediated by FRAP. α4 also binds to MID-1 and subsequently modulates PP2A function . Monoclonal Anti-α4 antibody is specific for human and mouse α4 (approx. 40 kDa).

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Application

Monoclonal Anti-α4 antibody is suitable for use in western blot (1-2 μg/mL using whole extracts of mouse 3T3 or human HeLa cells).

Price and Availability


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