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SAB4200299 Sigma

Anti-Contactin-2 (N-terminal antibody produced in rabbit

~1.5 mg/mL, affinity isolated antibody

Synonym: Anti-Contactin-2(axonal), Anti-AXT, Anti-Axonin-1, Anti-Cntn2, Anti-TAG-564, Anti-TAG1, Anti-Tax

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Properties

Related Categories Alphabetical Index, Antibodies, CO-CP, Primary Antibodies
species reactivity   human
application(s)   western blot: 1.5-3.0 μg/mL using HEK-293T cells overexpressing human contactin-2.
clone   polyclonal
concentration   ~1.5 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt ~135 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CNTN2(6900)
biological source   rabbit
conjugate   unconjugated

Description

Immunogen

Anti-Contactin-2 (N-terminal) antibody produced in rabbit specifically recognizes the N terminal region of human contactin-2.

synthetic peptide corresponding to a sequence at the N-terminal region of human contactin-2, conjugated to KLH. The corresponding sequence is highly conserved (single amino acid substitution) in rat and mouse contactin-2.

General description

Contactin-2 is a cell adhesion molecule produced abundantly in Purkinje cells that make up the distal component of cardiac conduction system. It is anchored to the cell membrane by glycan phosphatidyl inositol and is secreted into the extra cellular matrix.

Physical form

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.

Biochem/physiol Actions

Contactin-2 is a critical for neuronal patterning and ion channel clustering. It has key functions in neurogenesis and morphogenetic functions. Contactin-2 repairs the neurons and its expression increases highly post central nervous system injury.

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Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

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