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SAB4700541 Sigma

Anti-CD261, low endotoxin antibody, Mouse monoclonal

clone DR-4-02, purified immunoglobulin, buffered aqueous solution

Synonym: Anti-DR4, Anti-TNFRSF10A, Anti-TRAIL-R1

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Flow Cytometry, Antibodies to CD and Related Antigens, Primary Antibodies,
species reactivity   human
application(s)   flow cytometry: suitable
  immunocytochemistry: suitable
  immunoprecipitation: suitable
clone   DR-4-02, monoclonal
concentration   1 mg/mL
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgG1
shipped in   wet ice
storage temp.   2-8°C
Gene Information   human ... TNFRSF10A(8797)
biological source   mouse
impurities   ≤1 EU/μg endotoxin (LAL test)
conjugate   unconjugated
NCBI accession no.   NM_003844.3

Description

Immunogen

Fusion protein containing the extracellular part of TRAIL-R1 and the constant part of the heavy chain of the human IgG1

General description

The antibody DR-4-02 recognizes TRAIL-R1 (DR4), a human death receptor 4 (468 amino acids) expressed in most human tissues (spleen, peripheral blood leucocytes, thymus) and in a variety of tumour-derived cell lines.

Physical form

Solution in azide free phosphate buffered saline, pH 7.4; 0.2 um filter sterilized. Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.

Application

The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 3-5 μg/mL of sample. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

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