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SCP0004 Sigma

γ Secretase Inhibitor

≥95% (HPLC)

DOWNLOAD MSDS (PDF)

  • Empirical Formula (Hill Notation) C26H41N3O5

  • Molecular Weight 475.62

Properties

assay   ≥95% (HPLC)
form   lyophilized
composition   Peptide Content, ≥85%
storage condition   protect from light
storage temp.   −20°C

Description

Amino Acid Sequence

Z-Leu-Leu-Nle-al

Application

Gamma-secretase is a protein complex containing presenilin, nicastrin, APH-1, and PEN-2. The leupeptin analogue Z-Leu-Leu-Nle-al (N-benzyloxycarbonyl-Leu-Leu-norleucinal; Benzyloxicarbonyl-Leu-Leu-Nle-CHO (LLNle)) and closely related peptides are used as protease and a gamma secretase inhibitors.

Price and Availability

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