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SML0255 Sigma

4-DAMP

≥98% (HPLC)

Synonym: 1,1-Dimethyl-4-diphenylacetoxypiperidinium iodide, 4-Diphenylacetoxy-N-methylpiperidine methiodide, 4-[(Diphenylacetyl)oxy]-1,1-dimethyl-piperidinium iodide, 4-DAMP methiodide

  • CAS Number 1952-15-4

  • Empirical Formula (Hill Notation) C21H26INO2

  • Molecular Weight 451.34

  •  MDL number MFCD00078564

  •  PubChem Substance ID 329825263

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Properties

Related Categories Antagonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   WWJHRSCUAQPFQO-UHFFFAOYSA-M
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: ≥15 mg/mL
storage temp.   room temp

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

4-DAMP is a M3 preferring cholinergic receptor antagonist.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles

Articles

Acetylcholine Receptors (Muscarinic)

Muscarinic acetylcholine receptors are members of the superfamily of G protein-coupled receptors (GPCRs). They are relatively abundant and mediate many of the diverse actions of acetylcholine in the ...
Keywords: Alzheimer Disease, Apoptosis, Atomic absorption spectroscopy, Gene expression, Hormones, Molecular biology, Neurotransmitters, Parkinson Disease, Polymorphisms, Transduction

Discover Bioactive Small Molecules for Neuroscience

The nervous system, comprised of the brain and spinal cord (central nervous system, or CNS) and network of nerves that connects the CNS to the rest of the body (peripheral nervous system, or PNS) is ...
Keywords: Bioactive small molecules, Central Nervous System, Diseases, Metabolism, Neurodegenerative Diseases, Neuroscience, Neurotransmission, Neurotransmitters

Peer-Reviewed Papers
15

References

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