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SML0425 Sigma

Caspofungin diacetate

≥97% (HPLC)

Synonym: 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-(10,12-dimethyl-1-oxotetradecyl)-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-pneumocandin B0

  • CAS Number 179463-17-3

  • Empirical Formula (Hill Notation) C52H88N10O15 · 2C2H4O2

  • Molecular Weight 1213.42

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, C-CH, Cell Biology, Cell Signaling and Neuroscience,
assay   ≥97% (HPLC)
form   powder
color   white to beige
solubility   H2O: soluble15 mg/mL (clear solution)
shipped in   wet ice
storage temp.   −20°C

Description

Application

Caspofungin, aechinocandin, a lipophilic antifungal drug and α β-1,3-D-glucan synthesis antagonist, is used in fungal cell wall biosynthesis research to study the role of β-1,3-D-glucans in cell wall integrity and fungal survival under various environmental and chemical stresses.1

Biochem/physiol Actions

Caspofungin is an echinocandin antifungal that inhibits 1,3-β-D-glucan synthase, which is required for cell wall synthesis, thereby disturbing the integrity of the fungal cell wall.

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Safety & Documentation

Safety Information

WGK Germany 
3
RTECS 
TP8046500

Documents

Certificate of Analysis

Protocols & Articles

Articles

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Keywords: Antibiotics, Antifungals, Antivirals, Apoptosis, Bioactive small molecules, Cell signaling, Diabetes, Diseases, Immunology, Inflammation

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