SML0517 Sigma

Amlexanox

≥98% (HPLC)

Synonym: 2-Amino-7-(1-methylethyl)-5-oxo-5H-[1]Benzopyrano[2,3-b]pyridine-3-carboxylic acid, AA 673, Amoxanox, CHX 3673

  • CAS Number 68302-57-8

  • Empirical Formula (Hill Notation) C16H14N2O4

  • Molecular Weight 298.29

  •  MDL number MFCD00864790

Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Immune Cell Signaling and Blood, Immune System Regulation, Immunomodulators and Antibiotics More...
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: soluble10 mg/mL at warmed, clear
shipped in   wet ice
storage temp.   −20°C

Description

Biochem/physiol Actions

Amlexanox is an anti-allergy and anti-asthma drug that blocks histamine and leukotriene release from leukocytes and mast cells. Amlexanox has also been shown to inhibit cahaperone activity of Hsp90, and S100A13, which is involved in transport of proteins devoid of signal peptide sequences.

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