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SML1452 Sigma

Ibufenac

≥95% (HPLC)

Synonym: 4-(2-Methylpropyl)-benzeneacetic acid, 4-Isobutylphenylacetic acid

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Properties

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InChI Key   CYWFCPPBTWOZSF-UHFFFAOYSA-N
assay   ≥95% (HPLC)
form   powder
color   white to beige
solubility   DMSO: soluble20 mg/mL, clear
storage temp.   −20°C

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Ibufenac is a non-steroidal anti-inflammatory drug (NSAID) analog of ibuprofen that was withdrawn for hepatotoxicity. It inhibits cyclooxygenases COX-1 and -2 activity with IC50 values of 17.4 and 13.1 μM, respectively and > 40 μM for 5-LOX. It has been used in studies of drug-induced hepatotoxicity.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
AI4200000

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Certificate of Analysis

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