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SRP0114 Sigma

NCOR2/SMRT human

recombinant, expressed in E. coli, ≥60% (SDS-PAGE)

Synonym: Nuclear receptor corepressor 2, SMRTe, Silencing mediator of retinoic acid and thyroid hormone receptor, T3 receptor-associating factor, TRAC-1

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Properties

Related Categories Deacetylases, Epigenetics, Histone Modifying Enzymes, Molecular Biology, Proteins and Peptides for Epigenetic Research More...
recombinant   expressed in E. coli
assay   ≥60% (SDS-PAGE)
form   aqueous solution
mol wt   mol wt 39 kDa
NCBI accession no.   NM_006312
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... NCOR2(9612)

Description

Application

Useful for the study of enzyme kinetics, screening inhibitors and selectivity profiling.

General description

Human NCOR2/SMRT, DAD domain, amino acid 395-489, GenBank Accession No. NM_006312, N-terminal ST tag, MW = 39 kDa, expressed in E. coli system. NcoR2, nuclear receptor corepressor, are transcriptional corepressors.

Preparation Note

Thaw on ice. Upon first thaw, briefly spin tube containing enzyme to recover full content of the tube. Aliquot enzyme into single use aliquots. Store remaining undiluted enzyme in aliquots at -70°C. Note: Enzyme is very sensitive to freeze/thaw cycles.

Physical form

Formulated in 50 mM Tris-HCl, pH 8.0, 138 mM NaCl, 20 mM glutathione, and 10% glycerol.

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Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

Protocols & Articles
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