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SRP0159 Sigma

Histone H3 peptide (1-21) human

≥90% (HPLC)

Synonym: HIST1H3E, Histone H3.1

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Properties

Related Categories Cell Culture, Epigenetics, Growth Factors and Cytokines, Histones, Molecular Biology,
assay   ≥90% (HPLC)
form   aqueous solution
mol wt   mol wt ~2 kDa
NCBI accession no.   NM_003532
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... HIST1H3E(8353)

Description

Application

Study enzyme kinetics, and screen small molecular inhibitors of Histone 3, K4,K9, methyltransferases for drug discovery and HTS applications

Preparation Note

Thaw on ice. Upon first thaw, briefly spin tube to recover full content of the tube. Aliquot into single use aliquots. Store remaining product in aliquots at -70°C. Note: Avoid freeze/thaw cycles.

Physical form

Supplied as water solution, 800 μM

Price and Availability

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.

Documents

Certificate of Analysis

Protocols & Articles

Articles

Histone Modification and Chromatin Remodeling

Gene expression is governed by complex mechanisms including transcription factor binding to DNA and coordinated changes in chromatin structure. The primary protein components of chromatin are the his...
Savita Bagga, PhD.
BioFiles v7 n3, 2012, 10–16
Keywords: Acetylations, Amplification, Cancer, Cell culture, Chromatin immunoprecipitation, Cloning, DNA purification, Diseases, Gene expression, Immunoprecipitation, Indicators, Methylations, Microarray Analysis, PAGE, Polymerase chain reaction, Polymerase chain reaction - quantitative, Polymorphisms, Purification, Sequencing, Transcription, Whole genome amplification

Peer-Reviewed Papers
15

References

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