• USA Home
  • T0438 - Monoclonal Anti-Transforming Growth Factor-β1 antibody produced in mouse

T0438 Sigma

Monoclonal Anti-Transforming Growth Factor-β1 antibody produced in mouse

clone 9016.2, purified immunoglobulin, lyophilized powder

Synonym: Anti-TGF-β1



Related Categories Alphabetical Index, Antibodies, Antibodies for Apoptosis, Antibodies for Cell Biology, Antibodies for Hematopoietic Stem Cells,
species reactivity   rat, mouse, human
application(s)   capture ELISA: suitable
  immunohistochemistry: suitable
  neutralization: suitable
  western blot: suitable
clone   9016.2, monoclonal
antibody form   purified immunoglobulin
form   lyophilized powder
isotype   IgG1
storage temp.   −20°C
Gene Information   human ... TGFB1(7040)
mouse ... Tgfb1(21803)
rat ... Tgfb1(59086)
biological source   mouse
conjugate   unconjugated
Featured Industry   Research Pathology



purified, CHO cell-derived, recombinant TGF-β1 and latent TGF-β1.

General description

Transforming growth factor-β (TGF-β) belongs to the TGF-β superfamily of secreted proteins. TGF-β 1 exists as three isoforms TGF-β 1, TGF-β 2 and TGF-β 3. The TGF-β family is involved in a variety of signaling pathways that involve serine/threonine protein kinases. TGF-β acts through binding to three transmembrane receptors in mammals, type I, type II and type III receptors. The important pathways regulated by TGF-β are the SMAD, BMP, MAPK and PI3K/Akt pathways. TGF-β 1 is involved in cell and tissue differentiation, proliferation, inflammation, migration of monocytes, neutrophils and chemotaxis. Deregulation of TGF-β signaling has been implicated in many inflammation and autoimmune diseases. Monoclonal Anti-Transforming Growth Factor-β 1 antibody specifically reacts with human, mouse and rat TGF-β 1. The antibody shows less than 2% cross reactivity with TGF-β3 and TGF-β5 in ELISA.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.


By capture ELISA, <2% cross-reactivity is observed with TGF-β3 and TGF-β5.

Preparation Note

Purified using protein G


Anti-TGF-β I antibody may be used for immunoblotting at a working concentration of 1-2 μg/ml. The antibody may be used for ELISA as a capture antibody at a concentration of 1 μg/ml. A working antibody concentration of 8-25 μg/ml may be used for immunohistochemistry. For immunohistochemistry of corpus cavernosal biopsy tissue sections, a dilution of 1:50 was used.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Price and Availability

Antibody Explorer

Explore with Confidence

All labs need water
Safety & Documentation

Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  3
Protocols & Articles

Related Content

Antibody Explorer | Buy Primary & Secondary Antibodies

Monoclonal and polyclonal primary antibodies are focused on cell biology, neurobiology and molecular biology. Secondary antibodies targeting multiple host’s IgG are conjugated to alkaline phosphatase...
Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

Peer-Reviewed Papers


Related Products

related product

Product #


Add to Cart

92210 Timestrip Plus 0 °C

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?