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T0688 Sigma

Anti-Transforming Growth Factor-β1 antibody produced in chicken

affinity isolated antibody, lyophilized powder

Synonym: Anti-TGF-β1

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies against Cytokines, Chemokines, and Growth Factors for Stem Cell Biology, Antibodies against Cytokines/Growth Factors/Chemokines for Stem Cell Biology, Antibodies for Apoptosis,
species reactivity   human
application(s)   neutralization: suitable
  western blot: suitable
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... TGFB1(7040)
biological source   chicken
conjugate   unconjugated

Description

Immunogen

Recombinant human TGF-β1 expressed in CHO cells.

General description

Transforming Growth Factor-β1 (TGF β1) is a multifunctional protein that can stimulate or inhibit cellular proliferation. Mesenchymal origin cells are stimulated by TGF β1 while T and B lymphocytes, keratinocytes, hepatocytes and epithelial cells are inhibited by TGF β1. It facilitates in tissue growth and differentiation by participating in myogenesis, osteogenesis, adipogenesis, chondrogenesis, epithelial cell differentiation and immune cell function. Anti-Transforming Growth Factor-β1 antibody can be used in neutralization assay. Chicken anti-TGF β1 reacts specifically with recombinant human TGF-β1 or TGF-β1.2.

Physical form

Lyophilized from 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Specificity

The antibody will neutralize the biological activity of recombinant human TGF-β1 and porcine TGF-β1.2.

Application

Anti-Transforming Growth Factor-β1 antibody can be used in western blotting.

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Safety Information

Personal Protective Equipment  Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter
RIDADR  NONH for all modes of transport
WGK Germany  3
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Peer-Reviewed Papers
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