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T0875 Sigma

Sodium taurodeoxycholate hydrate

≥95% (TLC)

Synonym: 2-([3α,12α-Dihydroxy-24-oxo-5β-cholan-24-yl]amino)ethanesulfonic acid, Taurodeoxycholic acid sodium salt hydrate

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Properties

Related Categories Anionic Detergents, Bile Salts, Biochemicals and Reagents, Cell Culture, Core Bioreagents,
description   anionic
InChI Key   OLPIZAYYAVQETM-GGPRKOIFSA-M
assay   ≥95% (TLC)
mol wt   micellar avg mol wt 3100
aggregation number   6
CMC   1-4 mM(20-25°C)
mp   168 °C (dec.)(lit.)

Description

Application

Bile salt-related, anionic detergent used for isolation of membrane proteins including inner mitochondrial membrane proteins.

Sodium taurodeoxycholate hydrate has been used in a study to assess the effect of submicellar concentrations of bile salts on the lipid bilayer membrane. It has also been used in a study to investigate polymorphic behavior in protein-surfactant mixtures.

Packaging

1, 5, 25, 50, 100 g in poly bottle

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Fast and Robust HPLC Separation of Bile Acids and Conjugates with Ascentis Express C18

Bile acids are increasingly recognized as playing an important signaling role in the control of immune response and energy metabolism. Recently, there has been interest in measuring bile acid concent...
Clare Glicksman, Michael Wright, Dave Bell, and Anders Fridström
Reporter US, Volume 33.1
Keywords: Bacterial conjugations, Clinical, High performance liquid chromatography, Hormones, Mass spectrometry, Metabolism, Separation, Thin layer chromatography

LC/MS Analysis of Conjugated Bile Acids on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Conjugated Bile Acids on Ascentis® Express C18
Keywords: Chromatography, Clinical, High performance liquid chromatography, Mass spectrometry

Peer-Reviewed Papers
15

References

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