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T1427 Sigma

Triprolidine hydrochloride

Sigma Reference Standard

Synonym: (E)-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride, trans-2-[3-(1-Pyrrolidinyl)-1-p-tolylpropenyl]pyridine hydrochloride

  • CAS Number 6138-79-0

  • Empirical Formula (Hill Notation) C19H22N2 · HCl

  • Molecular Weight 314.85

  •  MDL number MFCD00039044

  •  PubChem Substance ID 329826672

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Properties

grade   Sigma Reference Standard
InChI Key   WYUYEJNGHIOFOC-NWBUNABESA-N
packaging   vial of 500 mg
solubility   H2O: moderately soluble
  ethanol: moderately soluble
  methanol: moderately soluble

Description

Biochem/physiol Actions

H1 histamine receptor antagonist.

Packaging

Supplied in amber screw-cap vials

Preparation Note

Triprolidine hydrochloride is moderately soluble in methanol, ethanol and water.

Application

Triprolidine hydrochloride has been used as a histamine H1 ligand to assess its affinity for [125I]-iodophenpropit binding sites. Furthermore, triprolidine has also been used to evaluate quantitative structure-retention relationships of antihistamine drugs chromatographed on α1-acid glycoprotein columns.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
UT7658000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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