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T1428 Sigma

apo-Transferrin bovine

BioReagent, suitable for cell culture, ≥98%

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Properties

Related Categories Albumins and Transport Proteins, Apo-Transferrin, Biochemicals and Reagents, Cell Culture, Plasma & Blood Proteins,
product line   BioReagent
assay   ≥98%
impurities   iron, essentially free
solubility   H2O: 10 mg/mL
suitability   suitable for cell culture
storage temp.   2-8°C

Description

Packaging

5, 10 g in poly bottle

50, 100, 500 mg in poly bottle

Application

All cells require iron for the proper uptake of oxygen from their environment. Transferrin, a protein isolated from serum, causes the uptake and transport of iron from culture medium to the cells. This allows proper oxygen uptake and also stimulates growth-related enzyme activity. Iron-saturated transferrin (holo transferrin) is continually recycled after releasing iron and becomes iron-deficient transferrin (apo-transferrin). Choosing which form to use depends upon the culture conditions. In media such as Dulbecco′s Modified Eagle′s Medium/Ham′s Nutrient Mixture F12 (DMEM/F12) that contain high levels of iron salt, using apo-transferrin is preferred.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Plasma Derived Proteins and Enzymes

Despite their complexity, blood and plasma are abundant biological resources for the discovery of drug targets and biomarkers for human disease. It is estimated that plasma may contain as many as 40,...
BioFiles 2006, 1.5, 2.
Keywords: Applications, Gas chromatography, Type

Peer-Reviewed Papers
15

References

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