|Related Categories||Angiogenesis, Angiogenesis Inhibitors, Angiogenesis Regulators, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules,|
45% (w/v) aq 2-hydroxypropyl-β-cyclode|
|DMSO: >20 mg/mL|
human ... LITAF(9516), TNF(7124)|
mouse ... Nos2(18126)
rat ... Nos1(24598)
(±)-Thalidomide selectively inhibits biosynthesis of tumor necrosis factor α (TNF-α); inhibitor of angiogenesis; immunosuppressive; sedative; teratogen.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. T144.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
Certificate of Analysis
|Precautionary statements||P280-P301 + P310|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T|
|Risk Statements (Europe)||46-61-21-25-62|
|Safety Statements (Europe)||53-22-26-36/37/39-45|
|RIDADR||UN 2811 6.1/PG 3|
Design, synthesis and antitumor evaluation of novel thalidomide dithiocarbamate and dithioate analogs against Ehrlich ascites carcinoma-induced solid tumor in Swiss albino mice. Magdy A-H Zahran et al Bioorg. Med. Chem. 16, 9708-18, (2008)
Mining biologically-active molecules for inhibitors of fatty acid amide hydrolase (FAAH): identification of phenmedipham and amperozide as FAAH inhibitors. Fabien Vincent et al Bioorg. Med. Chem. Lett. 19, 6793-6, (2009)
Synthesis and pharmacological evaluation of pyrazine N-acylhydrazone derivatives designed as novel analgesic and anti-inflammatory drug candidates. Yolanda Karla Cupertino da Silva et al Bioorg. Med. Chem. 18, 5007-15, (2010)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?