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T1512 Sigma

Tetramisole hydrochloride

phosphatase inhibitor

Synonym: (±)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride

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Properties

Related Categories Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Enzyme, Enzymes, Inhibitors, and Substrates, P to Q,
description   alkaline phosphatase inhibitor
InChI Key   LAZPBGZRMVRFKY-UHFFFAOYSA-N
mp   266-267 °C(lit.)

Description

Application

Suitable for inhibition of various mammalian alkaline phosphatases (i.e., liver, kidney, placenta, bone and tumor). Intestinal alkaline phosphatases are only slightly inhibited.

Structure-activity relationship for tetramisole derivatives as alkaline phosphatase inhibitors.

Other Notes

Racemic form of levamisole.

Packaging

2, 5, 10 g in poly bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


Biomedical Applications
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
NJ5950000
Protocols & Articles

Articles

Development of a Chiral Method for Levamisole and its Metabolite, Aminorex, for Monitoring Abuse in Horse Racing and Cocaine Adulteration

Concern over the abuse of amphetamines and other stimulants goes beyond its prevalence in the human population. Unscrupulous and unethical animal handlers administer drugs to their charges to enhance...
David S Bell, Denise Wallworth
Reporter US Volume 33.4
Keywords: Cardiovascular, Chiral resolution, High performance liquid chromatography, Inflammation, Mass spectrometry, Metabolites, Reductions, Separation

Peer-Reviewed Papers
15

References

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