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T1516 Sigma

DL-Trihexyphenidyl hydrochloride

solid

  • CAS Number 58947-95-8

  • Empirical Formula (Hill Notation) C20H31NO · HCl

  • Molecular Weight 337.93

  •  MDL number MFCD00058212

  •  PubChem Substance ID 24277876

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Properties

Related Categories Antagonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   QDWJJTJNXAKQKD-UHFFFAOYSA-N
form   solid
color   white
solubility   methanol: soluble50 mg/ml, clear to hazy, colorless
  H2O: soluble
Gene Information   human ... CHRM1(1128), CHRM2(1129), CHRM3(1131), CHRM4(1132), CHRM5(1133)

Description

Preparation Note

DL-Trihexyphenidyl hydrochloride is soluble in water. It dissolves in methanol at 50 mg/ml to yield a clear to hazy, colorless solution.

Application

DL-Trihexyphenidyl hydrochloride has been used to develop a capillary zone electrophoretic method with end-column electrochemiluminescence (ECL)-based detection technique.

Biochem/physiol Actions

DL-trihexyphenidyl hydrochloride (Benzhexol hydrochloride) is known to function as an antimuscarinic agent and a centrally acting anticholinergic. It can be used for controlling the symptoms of all Parkinsonism types, such as the idiopathic, and postencephalitic arteriosclerotic forms. Benzhexol hydrochloride exerts inhibitory functions on the parasympathetic nervous system.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

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Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
TN2625000

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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