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  • T1580 - Anti-TDP-43 (C-terminal) antibody produced in rabbit

T1580 Sigma

Anti-TDP-43 (C-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody, buffered aqueous solution

Synonym: Anti-ALS10, Anti-TARDBP, Anti-TARDP43



Related Categories ALS, Prion Disease, and Others, ALS, Prion Disease, and others, Alphabetical Index, Antibodies, Antibodies for Neurobiology,
species reactivity   human, rat, mouse
application(s)   immunohistochemistry: 5-10 μg/mL using rat, mouse, and human kidney
  indirect immunofluorescence: 5-10 μg/mL using human HepG2 cells
  western blot: 1-2 μg/mL using human U2OS cell lysates
clone   polyclonal
concentration   ~1.0 mg/mL
antibody form   affinity isolated antibody
form   buffered aqueous solution
mol wt   antigen mol wt ~43 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... TARDBP(23435)
biological source   rabbit
conjugate   unconjugated



synthetic peptide corresponding to amino acids 355-369 of human TDP-43, conjugated to KLH. The corresponding sequence is highly conserved (86% identity) in mouse TDP-43.

Physical form

Solution in 0.01 M phos­phate buffered saline, pH 7.4, containing 15 mM sodium azide.


Anti-TDP-43 antibody (C-terminal) produced in rabbit may be used to tag Tar DNA binding protein 43 (TDP-43, TARDP43, ALS10), a heterogeneous nuclear ribonucleoprotein (hnRNP), for detection and quantitation by Western blotting, immunoblotting or immunofluorescence and in tissue by immunohistochemical (IHC) techniques.

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunocytochemistry (1 paper)

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RIDADR  NONH for all modes of transport
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Keywords: Amplification, Buffers, Cell biology, Enzyme-linked immunosorbent assay, Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Molecular biology, Phosphorylations, Purification, Western blot

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