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T1692 Sigma

Tianeptine sodium salt hydrate

≥98% (HPLC), powder

Synonym: 7-[(3-Chloro-6,11-dihydro-6-methyl-dibenzo[c,f][1,2]thiazepine-11-yl)amino]heptanoic acid S,S dioxide sodium salt hydrate

  • CAS Number 30123-17-2 (anhydrous)

  • Empirical Formula (Hill Notation) C21H24ClN2NaO4S · xH2O

  • Molecular Weight 458.93 (anhydrous basis)

  •  PubChem Substance ID 24899985

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Description

Packaging

5, 25 mg in glass bottle

Preparation Note

Tianeptine sodium salt hydrate is soluble in DMSO at a concentration that is greater than or equal to 20 mg/ml.

Application

Sodium has been assayed as a steatosis-positive inducer in HepG2 cells. Tianeptine has also been used to study effects on rats exposed to swim endurance tests (SETs). This study reported that tianeptine increased swimming time in rats undergoing SET. Moreover, tianeptine also increased total cholesterol and LDL, while triglyceride levels were decreased. Thus, tianeptine may be involved in the pathogenesis of metabolic syndrome.

Features and Benefits

This compound was developed by Servier. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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