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T1775 Sigma

L-Thyroxine

powder, BioReagent, suitable for cell culture

Synonym: 3,3′,5,5″-Tetraiodo-L-thyronine, 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine, T4

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Properties

Related Categories Cell Culture, Hormones, Reagents and Supplements More...
InChI Key   XUIIKFGFIJCVMT-LBPRGKRZSA-N
product line   BioReagent
form   powder
potency   5-50 ng/mL
mp   223 °C (dec.)(lit.)
suitability   suitable for cell culture
Gene Information   human ... TTR(7276)
mouse ... Cnr2(12802)
rat ... Cnr1(25248)

Description

Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and, thus, protein synthesis.

Preparation Note

For long term storage, keep stock solutions at -20° in working aliquots and avoid repeated freeze/thaw cycles. Solutions stored at 2-8 °C are stable for up to 30 days.

Reconstitution

To prepare 20 μg/ml stock solution, dissolve in 50 ml sterile culture medium per mg thyroxine.

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
YP2833500

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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