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T2440 Sigma

Anti-Tumor Necrosis Factor Soluble Receptor II antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-TNF sRII

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Description

Immunogen

recombinant mouse TNF soluble receptor II (TNF sRII) expressed in Escherichia coli.

General description

Tumor Necrosis Factor Receptor II (TNF RII) is a 75kD transmembrane glycoprotein expressed mainly on endothelial cells, macrophages, Langerhans cells and monocytes. It has a crucial role in regulating TNF α function by antagonizing its biological activity that is by blocking TNF-α-induced apoptosis. Anti-Tumor Necrosis Factor Soluble Receptor II (TNF sRII) antibody can be used in western blotting. Goat anti-Tumor Necrosis Factor Soluble Receptor II antibody reacts specifically with mouse TNF sRII. This antibody has also shown less than 15% cross-reactivity for recombinant human TNF-sRII.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Specificity

The antibody detects mouse TNF RII and shows <15% cross-reactivity with recombinant human TNF sRII.

Application

Anti-Tumor Necrosis Factor Soluble Receptor II (TNF sRII) antibody can be used in indirect ELISA.

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RIDADR  NONH for all modes of transport
WGK Germany  3
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