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T2501 Sigma

L-Thyroxine sodium salt pentahydrate

≥98% (HPLC), powder

Synonym: 3-[4-(4-Hydroxy-3,5-diiodophenoxy)-3,5-diiodophenyl]-L-alanine sodium salt, Sodium levothyroxine, T4

  • CAS Number 6106-07-6

  • Linear Formula HOC6H2I2OC6H2I2CH2CH(NH2)COONa · 5H2O

  • Molecular Weight 888.93

  •  Beilstein Registry Number 5721845

  •  EC Number 200-221-4

  •  MDL number MFCD00149110

  •  PubChem Substance ID 24900041

  • Popular Documents:  FTNMR (PDF)  

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones, Other Protein/Peptide Hormones,
InChI Key   JMHCCAYJTTWMCX-QWPJCUCISA-M
assay   ≥98% (HPLC)
form   powder
mp   207-210 (dec.)(lit.)
storage temp.   −20°C
Gene Information   mouse ... Cnr2(12802)
rat ... Cnr1(25248)

Description

Biochem/physiol Actions

L-Thyroxine (T4) and triiodo-L-thyronine (T3) are iodine-containing hormones produced from thyroglobulin in the thyroid follicular cells. The stimulation of metabolic rate and regulation of growth and development by these hormones appear to be due to their effects on DNA transcription and thus, protein synthesis.

Packaging

1, 5 g in glass bottle

Preparation Note

L-Thyroxine sodium salt pentahydrate dissolves in 4 N NH4OH in methanol at 50 mg/ml to yield a clear to hazy, colorless to yellow solution.

Price and Availability


Amplified Detection

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Amicon Ultra Centrifugal Filters
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
YP2833760
Protocols & Articles
Peer-Reviewed Papers
15

References

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T0397 L-Thyroxine sodium salt pentahydrate, γ-irradiated, powder, BioXtra, suitable for cell culture
92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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