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T2780 Sigma

Monoclonal Anti-Tropomyosin antibody produced in mouse

clone TM311, ascites fluid


Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Actin-associated Proteins/Myosin, Antibodies to Cell and Organelle Proteins,
species reactivity   rabbit, pig, bovine, human, chicken, rat, mouse, hamster
application(s)   immunoprecipitation: suitable
  indirect ELISA: suitable
  indirect immunofluorescence: 1:400 using chicken fibroblasts
  microarray: suitable
  western blot: suitable using human tissue and chicken gizzard extracts
clone   TM311, monoclonal
antibody form   ascites fluid
isotype   IgG1
mol wt   antigen mol wt 36-39 kDa
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   bovine ... TPM1(281544)
chicken ... TPM1(396366)
human ... TPM1(7168)
mouse ... Tpm1(22003)
rat ... Tpm1(24851)
biological source   mouse
conjugate   unconjugated



chicken gizzard tropomyosin.

General description

Tropomyosin is a rigid rod shaped protein closely associated with actin filaments. Non-muscle forms of tropomyosin have been identified in a wide range of cell types. Tropomyosin together with troponin, regulate the binding of myosin to actin. Tropomyosin is a dimeric coiled-coil protein forming continuous polymers along the myosin-binding groove of actin. Varoius tropomyosin isoforms help to confer structure and function to actins in the cytoskeleton and in striated muscle function.


Mouse monoclonal clone TM311 anti-Tropomyosin antibody is used to tag tropomyosin for detection and quantitation by immunocytochemical and immunohistochemical (IHC) techniques such as immunoblotting, immunoprecipitation, and immunofluorescence. It is used as a probe to determine the presence and roles of tropomyosin in cytoskeletal structures.

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