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T2928 Sigma

Monoclonal Anti-Tyrosine Hydroxylase antibody produced in mouse

clone TH-16, ascites fluid

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Neurobiology, Antibodies for Neurotransmission, Antibodies for Neurotransmitter Synthesis and Metabolism,
species reactivity   rabbit, rat, guinea pig, bovine, sheep, human, monkey
application(s)   immunohistochemistry: suitable
  immunoprecipitation: suitable using native or SDS-denatured TH.
  microarray: suitable
  western blot: 1:8,000 using extracts of cultured rat adrenal pheochromocytoma (PC12) cells.
clone   TH-16, monoclonal
antibody form   ascites fluid
isotype   IgG1
contains   15 mM sodium azide
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... TH(7054)
rat ... Th(25085)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

rat tyrosine hydroxylase (TH).

Specificity

The antibody recognizes an epitope present in the N-terminal region (between aa 40-152) of both rodent and human tryosine hydroxylase. TH-16 detects both the intact subunits and the 59/57 kDa doublet and an array of decreasing molecular weight TH forms resulting from severe proteolysis.

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