Synonym: 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethyl-imidacarbocyanine iodide, 5,5′,6,6′-Tetrachloro-1,1′,3,3′-tetraethylbenzimidazolocarbocyanine iodide, CBIC2(3)
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A dual-emission potential-sensitive probe that can be used to measure mitochondrial membrane potential. JC-1 is a green-fluorescent (λex 520 nm) monomer at low membrane potential. At higher potentials, JC-1 forms red-fluorescent (λem 596 nm ) "J-aggregates," which exhibit broad excitation and very narrow emission spectra. The ratio of red to green fluorescence of JC-1 is dependent only on membrane potential, and not influenced by mitochondrial size, shape, or density.
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≥97% (TLC), powder
kit sufficient for 50 reactions (in a 2 mL cuvette), kit sufficient for 1,000 reactions (using 96 multiwell plates)
sufficient for 10-20 g (animal tissue), sufficient for 50 assays (2 mL), isolation of enriched mitochondrial fraction from animal tissues
kit sufficient for 40 tests (of 5 mL cell suspensions), kit sufficient for 200 tests (of 1 mL cell suspensions)
In 1998 R.F. Furchgott, L.J. Ignarro, and F. Murad received the Nobel Prize in Physiology and Medicine for their discoveries concerning nitric oxide as a signaling molecule in the cardiovascular syst...
BioFiles 2011, 6.3, 23.
Keywords: Biochemistry, Biological processes, Cancer, Cardiovascular, Central Nervous System, Diseases, Extinction coefficient, Indicators, Inflammation, Microscopy, Neurotransmission, Sol-gel
Short-term Salinity Stress In Tobacco Plants Leads To The Onset Of Animal-like PCD Hallmarks In Planta In Contrast To Long-term Stress. Andronis, E.A., and Roubelakis-Angelakis, K.A. Planta 231, 437-48, (2010)
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|CS0390||Mitochondria Staining Kit, kit sufficient for 40 tests (of 5 mL cell suspensions), kit sufficient for 200 tests (of 1 mL cell suspensions)|
|CS0760||Isolated Mitochondria Staining Kit, kit sufficient for 50 reactions (in a 2 mL cuvette), kit sufficient for 1,000 reactions (using 96 multiwell plates)|
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