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T4192 Sigma

Tyrphostin SU 1498

≥98%

Synonym: (E)-N-(3″-Phenylpropyl)-α-cyano-3′,5′-diisopropyl-4′-hydroxycinnamamide

  • Empirical Formula (Hill Notation) C25H30N2O2

  • Molecular Weight 390.52

  •  MDL number MFCD03453026

  •  PubChem Substance ID 24900199

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Description

Biochem/physiol Actions

Potent and selective inhibitor of the VEGF receptor kinase, Flk-1. Very weak inhibitor of PDGFR-kinase, EGFR-kinase and HER-2 kinase.

Preparation Note

Tyrphostin SU 1498 is soluble in DMSO.

Application

Tyrphostin SU 1498 has been used as a VEGF inhibitor in mice1.

Price and Availability


All labs need water

Biomedical Applications
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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