T4192
Sigma
Tyrphostin SU 1498
≥98%
DOWNLOAD MSDS (PDF)Synonym: (E)-N-(3″-Phenylpropyl)-α-cyano-3′,5′-diisopropyl-4′-hydroxycinnamamide
-
Empirical Formula (Hill Notation) C25H30N2O2
-
Molecular Weight 390.52
-
MDL number MFCD03453026
-
PubChem Substance ID 24900199
Properties
| Related Categories | Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Enzyme Inhibitors, |
| assay | ≥98% |
| potency | 700 nM IC50 |
| solubility | DMSO: soluble |
| storage temp. | −20°C |
Description
Biochem/physiol Actions
Potent and selective inhibitor of the VEGF receptor kinase, Flk-1. Very weak inhibitor of PDGFR-kinase, EGFR-kinase and HER-2 kinase.
Price and Availability
Related Papers
Flk-1 as a target for tumor growth inhibition. Strawn, L.M., et al. Cancer Res. 56, 3540, (1996)
Technical Service:
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Bulk Ordering & Pricing:
Need larger quantities for your development, manufacturing or research applications?
