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T4442 Sigma

Anti-Transforming Growth Factor-β2 antibody produced in goat

affinity isolated antibody, lyophilized powder

Synonym: Anti-TGF-β2

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies against Cytokines, Chemokines, and Growth Factors for Stem Cell Biology, Antibodies against Cytokines/Growth Factors/Chemokines for Stem Cell Biology, Antibodies for Cell Biology,
species reactivity   pig, human
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
  neutralization: suitable
  western blot: 0.1-0.2 μg/mL
clone   polyclonal
antibody form   affinity isolated antibody
form   lyophilized powder
storage temp.   −20°C
Gene Information   human ... TGFB2(7042)
biological source   goat
conjugate   unconjugated
Featured Industry   Research Pathology

Description

Immunogen

porcine transforming growth factor-β2.

General description

Transforming Growth Factor-β 2 (TGF-β 2) is a protein produced by many cells and is found in the highest concentration in mammalian bone and porcine platelets. In body fluids like breast milk, amniotic fluid as well as the aqueous and vitreous humor of the eye, the prominent form exist is Latent TGF-β2. It has a pivotal role in regulating invasion in high-grade gliomas by inducing mesenchymal phenotype and remodeling the extracellular matrix. Anti-Transforming Growth Factor-β2 antibody can be used in neutralization and immunohistochemistry. Goat anti-TGF-β 2 antibody reacts specifically with human and porcine TGF-β 2 and TGF-β 1.2. The product has also shown less than 2% cross-reactivity for TGF-β 1, TGF-β 3 and TGF-β 5.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline containing carbohydrates.

Specificity

The antibody recognizes TGF-β2 and TGF-β1.2. By immunoblotting (non-reducing conditions) and ELISA, the antibody shows less than 2% cross-reactivity with TGF-β1, TGF-β3, and TGF-β5.

Application

Anti-Transforming Growth Factor-β2 antibody can be used in western blotting and ELISA.

Price and Availability


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Safety & Documentation

Documents

Certificate of Analysis

Certificate of Origin

Safety Information

RIDADR  NONH for all modes of transport
WGK Germany  3
Protocols & Articles

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Peer-Reviewed Papers
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References

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