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T4557 Sigma

Thapsigargicin

≥90%

  • CAS Number 67526-94-7

  • Empirical Formula (Hill Notation) C32H46O12

  • Molecular Weight 622.70

  •  MDL number MFCD00214081

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Intracellular Calcium Regulators, Intracellular Calcium Signaling
InChI Key   LXWLOFYIORKNSA-FFOGNQQCSA-N
assay   ≥90%
storage temp.   −20°C

Description

Linkage

Less potent and less hydrophobic analog of thapsigargin.

Application

Thapsigargicin has been assayed as a potential inhibitor of S. mansoni ATPdiphosphohydrolases (ATPDase)2.

Biochem/physiol Actions

Thapsigargicin is known to mobilize intracellular Ca2+. Furthermore, studies have reported that thapsigargicin can induce the release of histamine from pulmonary, mesentery and cardiac mast cells of rats3.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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