• USA Home
  • T4577 - Terodiline hydrochloride

EMAIL THIS PAGE TO A FRIEND
T4577 Sigma

Terodiline hydrochloride

≥98% (HPLC), solid

Synonym: Bicor, N-(1,1-Dimethylethyl)-alpha-methyl-gamma-phenylbenzenepropamine hydrochloride

  • CAS Number 7082-21-5

  • Empirical Formula (Hill Notation) C20H27N·HCl

  • Molecular Weight 317.90

  •  MDL number MFCD00941402

Purchase

Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Calcium Antagonists, Cell Biology, Cell Signaling and Neuroscience,
InChI Key   RNGHAJVBYQPLAZ-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
color   white to off-white
solubility   DMSO: >20 mg/mL
storage temp.   −20°C

Description

Biochem/physiol Actions

Terodiline is known to increase corrected QT interval (QTc) and decrease resting heart rate in elderly patients. Furthermore, terodiline hydrochloride has been linked to cardiac arrhythmias1.

Terodiline hydrochloride is a non-selective calcium channel antagonist with anticholinergic and vasodilatory activity.

Preparation Note

Terodiline hydrochloride is soluble in DMSO at a concentration that is greater than 20 mg/ml.

Features and Benefits

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Price and Availability


DISCOVER Bioactive Small Molecules

All labs need water
Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
UH9970000

Documents

Certificate of Analysis

Protocols & Articles

Articles

Calcium Channels

The voltage-gated calcium channels constitute one group of a superfamily of ion channels that also includes sodium and potassium channels and amongst which exists functional, sequence and topological...
Keywords: Cardiovascular, Clinical, Diabetes, Gene expression, Hormones, Ligands, Neurotransmitters

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?