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T4661 Sigma

Trizma® base

≥99.9% (titration), crystalline

Synonym: 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Tris(hydroxymethyl)aminomethane, Trometamol

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Properties

Related Categories Biochemicals and Reagents, Biological Buffers, Buffers A to Z, Good’s Buffers
Quality Level   ELITE
description   aminopeptidase substrate
InChI Key   LENZDBCJOHFCAS-UHFFFAOYSA-N
assay   ≥99.9% (titration)
form   crystalline
loss   ≤5% (loss on drying, 110 °C)
color   white
pH   10.0-11.5
useful pH range   7 - 9
pKa (25 °C)   8.1
bp   219-220 °C/10 mmHg(lit.)
mp   167-172 °C(lit.)
solubility   water: soluble (400 g plus 600 mL of water)
λ   (290nm < 0.05)
  in 5 mM Tris; DNA (40% (w/w))
Featured Industry   Diagnostic Assay Manufacturing

Description

Analysis Note

Not pyrogen tested. Certificates of analysis are available with lot specific information.

Other Notes

The pH values of all buffers are temperature- and concentration-dependent. For Tris buffers, pH increases about 0.03 unit per °C decrease in temperature, and decreases 0.03-0.05 unit per ten-fold dilution.
For precise applications, use a carefully calibrated pH meter with a glass/calomel combination electrode.

Packaging

1 kg in poly bottle

Meets all specifications for T1503. For biotechnology, diagnostics or manufacturing use. Please inquire for commercial quantities.

100 g in poly bottle

5 kg in poly drum

Legal Information

Trizma is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability


Laboratory Gloves

Tris Always Available

Interactive Buffer Table
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
TY2900000
Protocols & Articles

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Peer-Reviewed Papers
15

References

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