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T6137 Sigma

Trioxsalen

≥98% (HPLC), powder

Synonym: 2,5,9-Trimethylfuro[3,2-g]benzopyran-7-one, 4,5′,8-Trimethylpsoralen, TMP, Trisoralen

Properties

Related Categories Apoptosis and Cell Cycle, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology,
assay   ≥98% (HPLC)
form   powder
color   white
mp   229-231 °C(lit.)
solubility   chloroform: soluble50  mg/mL, clear, colorless to faintly yellow
fluorescence   λex 269 nm; λem 445 nm in methanol
  λex 321 nm; λem 445 nm (bound to DNA in Tris, pH 8.1)
storage temp.   −20°C

Description

Packaging

1 g in glass bottle

100, 500 mg in glass bottle

Preparation Note

Trioxsalen is soluble in chloroform at 50 mg/ml and yields a clear, colorless to faint yellow solution.

Application

Trioxsalen has been used for mutagenesis of N2 worms4,5.

Biochem/physiol Actions

Photochemical crosslinker of DNA that has been used as a probe for nucleic acid structure and function. Trioxsalen has also been used to crosslink DNA onto mica surfaces.

Features and Benefits

This compound was developed by Valeant. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Price and Availability

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