T6397 Sigma

3,3′,5-Triiodo-L-thyronine sodium salt

powder, BioReagent, suitable for cell culture

Synonym: Liothyronine, O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine sodium salt, T3


Related Categories Bioactive Small Molecules, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones,
product line   BioReagent
assay   ≥95%
form   powder
potency   0.02-50 ng/mL (lit.)
suitability   suitable for cell culture
storage temp.   −20°C
Gene Information   human ... THRA(7067), THRB(7068)
rat ... Thra(81812), Thrb(24831)


Biochem/physiol Actions

T3 is a thyroid hormone that increases rates of proteins synthesis, stimulates the breakdown of cholesterol, and effects embryonic development. In cell culture, T3 regulates cell differentiation and protein expression.


To prepare 20 μg/ml stock solution: add 1ml 1N NaOH per mg 3,3′, 5-triiodo-L-thyronine; gently swirl to dissolve. To this, add 49 ml sterile medium per ml 1N NaOH added.

Physical form

powder-0 °C; stock-frozen in working aliquots, avoid repeated freeze/thaw, solution stable 2-8 °C, 30 days

Price and Availability

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