Synonym: SBTI
CAS Number 9035-81-8
MDL number MFCD00082103
Popular Documents: Product Information Sheet (PDF)
| Related Categories | Application Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology, Cell Culture, |
| sterility | sterile-filtered |
| product line | BioReagent |
| form | solution |
| concentration | 1 × |
| impurities | endotoxin, tested |
| suitability | suitable for cell culture |
| shipped in | dry ice |
Optimized for passage of endothelial cell cultures.
Contains chromatographically purified soybean trypsin inhibitor and iron supplemented calf serum.
View more information on Trypsin Inhibitor.
Prepared in Dulbecco′s Phosphate Buffered Saline without calcium and magnesium.
Trypsin inhibitor is soluble in water and phosphate buffers at concentrations of 10 mg/ml or higher. Solutions at higher concentrations may be hazy and have a yellow to amber color.
Soybean trypsin inhibitor inhibits trypsin and to a lesser extent chymotrypsin and plasmin. It forms a 1:1 stoichiometric complex with trypsin. Upon formation of this complex, trypsin may cleave a single arginine-isoleucine bond in the inhibitor. Dissociation of this complex may yield the modified form or the native inhibitor. At the optimal pH for trypsin binding (pH 8.0), the association constant is ≥ 10x108.
Soybean trypsin inhibitor exhibits a high degree of sequence homology with cathepsin D inhibitor from potatoes.1
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