|Related Categories||Antibacterial, Antibiotic powders, Antibiotics, Antibiotics A to Z, Antibiotics T-Z,|
|solubility||H2O: soluble10 mg/mL (as a stock solution. Stock solutions should be filtered sterilized and stored at −20°C. Stable at 37°C for 4 days.)|
|suitability||suitable for cell culture|
Used in tetracycline controlled gene expression systems (gene switches) such a the tet-on and tet-off systems. Recommended for use in cell culture applications at 10 mg/L.
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Resistance: Loss of cell wall permeability.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||36/37/38|
|Safety Statements (Europe)||26-36|
1Application Key: CC = Callus Culture; PR = plant regeneration; EC = cotyledon, hypocotyl, or leaf disc culture; TS = transformant selection; SE = somatic embryogenesis; SSC = stem selection culture;...
Keywords: Antibiotics, Cell culture
Quantitative real-time PCR study of the expression and regulation of the tetracycline resistance gene in Riemerella anatipestifer. Zhong CY, Cheng AC, Wang MS, et al. Poult. Sci. 92(6), 1552-9, (2013)
Association of a probiotic to a Helicobacter pylori eradication regimen does not increase efficacy or decreases the adverse effects of the treatment: a prospective, randomized, double-blind, placebo-controlled study. Navarro-Rodriguez T, Silva FM, Barbuti RC, et al. BMC Gastroenterol. 13, 56, (2013)
Prevalence of tetracycline resistance genes and identification of tet(M) in clinical isolates of Escherichia coli from sick ducks in China. Hu GZ, Pan YS, Wu H, et al. J. Med. Microbiol. 62(Pt 6), 851-8, (2013)
Neisseria gonorrhoeae antimicrobial resistance among men who have sex with men and men who have sex exclusively with women: the Gonococcal Isolate Surveillance Project, 2005-2010. Kirkcaldy RD, Zaidi A, Hook EW, et al. Ann. Intern. Med. 158(5 Pt 1), 321-8, (2013)
Deglycosylation as a mechanism of inducible antibiotic resistance revealed using a global relational tree for one-component regulators. Cuthbertson L, Ahn SK, and Nodwell JR Chem. Biol. 20(2), 232-40, (2013)
Toxicity of five antibiotics and their mixtures towards photosynthetic aquatic organisms: implications for environmental risk assessment. González-Pleiter M, Gonzalo S, Rodea-Palomares I, et al. Water Res. 47(6), 2050-64, (2013)
Aptamer based extraction followed by electrospray ionization-ion mobility spectrometry for analysis of tetracycline in biological fluids. Aslipashaki SN, Khayamian T, and Hashemian Z J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 925, 26-32, (2013)
Contemporary potencies of minocycline and tetracycline HCL tested against Gram-positive pathogens: SENTRY Program results using CLSI and EUCAST breakpoint criteria. Jones RN, Wilson ML, Weinstein MP, et al. Diagn. Microbiol. Infect. Dis. 75(4), 402-5, (2013)
Pharmacokinetics and residues of tetracycline in crucian carp muscle using capillary electrophoresis on-line coupled with electrochemiluminescence detection. Deng B, Xu Q, Lu H, et al. Food Chem. 134(4), 2350-4, (2012)
Doxycycline-regulated 3T3-L1 preadipocyte cell line with inducible, stable expression of adenoviral E4orf1 gene: a cell model to study insulin-independent glucose disposal. Krishnapuram R, Dhurandhar EJ, Dubuisson O, et al. PLoS ONE 8(3), e60651, (2013)
Synergistic interactions of epigallocatechin gallate and oxytetracycline against various drug resistant Staphylococcus aureus strains in vitro. Novy P, Rondevaldova J, Kourimska L, et al. Phytomedicine 20(5), 432-5, (2013)
Synthesis, characterization, and liposome partition of a novel tetracycline derivative using the ionic liquids framework. Alves F, Oliveira FS, Schröder B, et al. J. Pharm. Sci. 102(5), 1504-12, (2013)
Aldrich MSDS 1, 1654:B / Corp MSDS 1 (2), 3252:B / FT-IR 1 (2), 421:C / FT-IR 2 (2), 3103:A / RegBook 1 (2), 2097:M / Sax 6, 2521 / Sigma FT-IR 1 (1), 720:D / Structure Index 1, 332:C:1
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