Tetracycline hydrochloride
powder, BioReagent, suitable for cell culture
DOWNLOAD MSDS (PDF)-
CAS Number 64-75-5
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Empirical Formula (Hill Notation) C22H24N2O8 · HCl
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Molecular Weight 480.90
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Beilstein Registry Number 3844873
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EC Number 200-593-8
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MDL number MFCD00078142
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PubChem Substance ID 24900468
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Popular Documents: Specification Sheet (PDF) | FTIR (PDF)
Properties
| Related Categories | Antibacterial, Antibiotic powders, Antibiotics, Antibiotics A to Z, Antibiotics T-Z, |
| product line | BioReagent |
| form | powder |
| impurities | endotoxin, tested |
| mp | 220-223 °C(lit.) |
| solubility | H2O: soluble10 mg/mL (as a stock solution. Stock solutions should be filtered sterilized and stored at −20°C. Stable at 37°C for 4 days.) |
| suitability | suitable for cell culture |
| storage temp. | −20°C |
Description
Application
Used in tetracycline controlled gene expression systems (gene switches) such a the tet-on and tet-off systems. Recommended for use in cell culture applications at 10 mg/L.
Biochem/physiol Actions
Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit.
Antimicrobial spectrum: Gram-negative and Gram-positive bacteria.
Mode of Resistance: Loss of cell wall permeability.
Protocols & Applications
Price and Availability
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