T7665 Sigma

Tyrphostin 51


Synonym: 2-Amino-1,1,3-tricyano-4-(3′,4′,5′-trihydroxyphenyl)butadiene



Biochem/physiol Actions

EGFR tyrosine kinase inhibitor.

Tyrphostin 23 is a small molecule inhibitor of epidermal growth factor (EGF) receptor kinase function. This molecule associates with the substrate subsite of the protein tyrosine kinase (PTK) domain,.


25 mg in poly bottle

5 mg in glass bottle

Preparation Note

5 mg of Tyrphostin 51 is soluble in 0.1 ml of DMSO and yields a clear, orange to red solution.


Tyrphostin 51 has been used to study the inhibition of rat hepatic leptin 1.

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Safety Information

NONH for all modes of transport
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