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T7941 Sigma

Monoclonal Anti-β-Tubulin IV antibody produced in mouse

clone ONS.1A6, ascites fluid

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Cell and Organelle Proteins, Antibodies to Cytoskeleton,
species reactivity   human, hamster, chicken, bovine, rat, mouse
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
  indirect ELISA: suitable
  microarray: suitable
  western blot: 1:400 using cultured human breast adenocarcinoma cell line MCF-7
clone   ONS.1A6, monoclonal
antibody form   ascites fluid
isotype   IgG1
mol wt   antigen mol wt ~55 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... TUBB4(10382)
mouse ... Tubb4(22153)
rat ... Tubb4(29213)
biological source   mouse
conjugate   unconjugated

Description

Immunogen

synthetic peptide corresponding to the C-terminal sequence of β-tubulin isotype IV, conjugated to BSA.

General description

Microtubules are heterodimeric proteins that comprise of α- and β-tubulins. β-tubulins have four different isotypes in brain cells, ranging from β I to β IV . Anti-tubulin antibodies are useful to study the localization of tubulin proteins. Monoclonal Anti-β-Tubulin IV antibody is specific for epitope located in the C-terminal sequence of β-tubulin isotype IV in humans, bovines, hamsters, rats, mice and chickens. The product does not react with other tubulin isotypes.

Application

Monoclonal Anti-β-Tubulin IV antibody is suitable for use in immunohistochemistry (formalin-fixed, paraffin-embedded sections), indirect ELISA, microarray and western blot (1:400 using cultured human breast adenocarcinoma cell line MCF-7). The product may also be used for immunocytochemistry and immunofluorescence .

Price and Availability


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