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T7947 Sigma

(R)-Tomoxetine hydrochloride

solid

Synonym: (R)-N-Methyl-γ-(2-methyl­phenoxy)benzenepropanamine hydrochloride, Atomoxetine hydrochloride

  • CAS Number 82248-59-7

  • Empirical Formula (Hill Notation) C17H21NO · HCl

  • Molecular Weight 291.82

  •  MDL number MFCD06410992

  •  PubChem Substance ID 24278760

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Description

Biochem/physiol Actions

Norepinephrine uptake blocker.

Application

(R)-Tomoxetine hydrochloride has been used to study the role of L-DOPS (L-threo-3,4-dihydroxyphenylserine) in the pathogenesis of Alzheimer′s disease in mice.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

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Peer-Reviewed Papers
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