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T8157 Sigma

Testosterone β-D-glucuronide sodium salt

Synonym: 17β-Hydroxy-4-androsten-3-one 17-D-glucuronide, 4-Androsten-17β-ol-3-one 17-glucuronide

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Properties

Related Categories Androgen, Cell Biology, Cell Signaling and Neuroscience, Cytokines, Growth Factors and Hormones, Hormones,
InChI Key   JUXKYFINRYJTDA-CLDJTUICSA-M
drug control   USDEA Schedule III; Home Office Schedule 4.2; regulated under CDSA - not available from Sigma-Aldrich Canada
solubility   ethanol: water (1:1): soluble10 mg/mL, clear, colorless
storage temp.   −20°C

Description

Preparation Note

Testosterone β-D-glucuronide sodium is soluble in a solvent mixture of ethanol and water (1:1) at 10 mg/ml and yields a clear, colorless solution.

Application

Testosterone has been used as a substrate for UDP-glucuronyltransferase-based drug metabolism assays using microsome-encapsulation techniques.

Biochem/physiol Actions

Androgens direct the development of the male phenotype during embryogenesis and at puberty. Testosterone is an androgen that is secreted by the testis. This hormone is converted to dihydrotestosterone in the target tissues where it may mediate several biological functions.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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