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T8819 Sigma

TFIIB human

~5 units/μL, recombinant, expressed in E. coli, solution

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Properties

Related Categories Cell Biology, Cell Signaling and Neuroscience, Gene Regulation and Expression, Transcription Factors
recombinant   expressed in E. coli
form   solution
mol wt   mol wt ~32 kDa
concentration   ~5 units/μL
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... GTF2B(2959)

Description

Packaging

50 units in glass bottle

Unit Definition

One gel shift unit is the amount of TFIIB required to form 0.2 pmol of TFIIB/TFIID/DNA complex as detected by gel shift.

Physical form

Solution in 20 mM Tris-HCl, pH 7.4, 100 mM NaCl, 2 mM DTT, 1 mM EDTA, 0.1% Triton® X-100.

Biochem/physiol Actions

General transcription factor for RNA Polymerase II.

The amino terminal region of TFIIB contains a zinc ribbon fold composed of antiparallel Β strands. Mutational studies show that this domain is required for recruitment of RNA Pol II for transcriptional initiation.

Price and Availability


All labs need water
Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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