|Related Categories||Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Antifungal, Antimycobacterial,|
Mode of Action: Inhibits squalene epoxidase, preventing biosynthesis of ergosterol.
Antimicrobial spectrum: Antifungal and antimycotic. Fungicidal against dermatopytes and some yeasts; fungistatic against Candida albicans.
Terbinafine inhibits squalene monooxygenase thereby blocking the biosynthesis of ergosterol, which is an essential component of fungal cell membranes. The inhibition of squalene monooxygenase also results in the accumulation of squalene. Terbinafine hydrochloride is highly lipophilic and tends to accumulate in skin, nails, and fatty tissues1. It is antifungal and antimycotic. It is fungicidal against dermatopytes and some yeasts and is fungistatic against Candida albicans.
Terbinafine hydrochloride is a synthetic allylamine antifungal. It is used to treat dermatophyte infections of the toenail/fingernail, ringworm and jock itch1. It is used in adsorption, partition and stability studies2,3.
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P261-P273-P305 + P351 + P338-P501|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi,N|
|Risk Statements (Europe)||36/37/38-50/53|
|Safety Statements (Europe)||26-60-61|
|RIDADR||UN 3077 9/PG 3|
Antifungal compounds have been overshadowed by antibacterials in research interest and application due to the greater impact bacterial infections have had on health. Resistance to antibacterial drugs...
BioFiles 2009, 4.3, 10.
Keywords: Antibiotics, Antifungals, Cellular processes, Clinical, Fungicides, Gene expression, Transcription
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?